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We have recently completed a prospective randomized feasibil
2019-05-07
We have recently completed a prospective randomized feasibility study of de-escalated bisphosphonate treatment with intravenous pamidronate in patients with metastatic breast cancer to bone [7]. Here we report on an analysis utilizing data from this trial aimed at comparing BPI and FACT-BP and to co
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El valor testimonial de Tampico sin duda
2019-05-07
El valor testimonial de Tampico sin duda desborda las intenciones de su exquisito autor, quien se sentía más order Fmoc-Ser(tBu)-OH gusto describiendo las finas maderas de los muebles de su casa, que padeciendo el asedio de la incomodidad, el calor y los mosquitos de los pueblos del Golfo de México.
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br VI Realmente lo parad jico de
2019-05-06
VI. Realmente lo paradójico de la fiesta del Corpus y de su poder de convocatoria en tierras andinas no residirá en las aguas turbulentas de disensiones interétnicas que alteran una paz sólo de superficie, tampoco en el discurso que pretendía enseñarla ibuprofen msds nativos legos, sino en esta p
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A partir de las consideraciones que distinguen la institucio
2019-05-06
A partir de las consideraciones que distinguen la institucionalización formal e informal, O’Donnell hace un llamado VE-822 tener en cuenta las especificidades de las democracias de América Latina y plantea que algunas democracias han subsistido, se han mantenido en el tiempo aun con la presencia de
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Como observa Drnas de Cl ment los estados
2019-05-06
Como observa Drnas de Clèment, los estados donde se encuentran los acuíferos generalmente son renuentes RVX-208 cost aceptar que se trata de recursos compartidos, e intentan aprovechar el recurso de manera desmedida y en perjuicio del Estado vecino. Así, se podrían identificar al menos dos puntos de
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Fig shows different PVCs observed before PVC and after
2019-05-06
Fig. 4 shows 2 different PVCs observed before (PVC 1) and after the application of radiofrequency dhpg (PVC 2) in patient 17. After ablation of PVC 1, a different PVC (PVC 2) with a slightly different QRS morphology from that of PVC 1 was observed. Fig. 5 shows the activation sequence of PVC 1 and t
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In this section we will try
2019-05-06
In this section we will try and address many of the frequently asked questions around preventive and prophylactic measures for patients either starting or already established on bone-targeted therapy (Figs. 2 and 3). In view of the difficulties in treating ONJ, preventive strategies would seem to ma
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Introduction Neuroblastoma NB which arises from embryonal ne
2019-05-06
Introduction Neuroblastoma (NB), which arises from embryonal neural crest cells, is the most common extra-cranial solid tumor of childhood and accounts for more than 15% of all child cancer death [1,2]. Patients with NB frequently manifest disseminated disease at first visit and prognosis of these
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br Discussion and outstanding questions Reproductive endocri
2019-05-06
Discussion and outstanding questions Reproductive endocrine hormones such as inhibin affect breast cancer cell survival in the primary tumour and affect tumour homing and survival in the bone microenvironment. The molecular mechanism driving this effect of hormones in bone is likely to be multifa
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br Introduction Magnetic resonance imaging MRI has great uti
2019-05-06
Introduction Magnetic resonance imaging (MRI) has great utility in evaluating musculoskeletal tumors. However, some lesions have an appearance on MRI that make it challenging to differentiate benign from malignant lesions. Even intravenous (IV) TAK-242 sometimes does not allow differentiation of
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Argentina adopta una posici n semejante
2019-05-05
Argentina adopta una posición semejante sodium channel blocker los anteriores países, Aborda el principio en la Ley 25675, incorpora un seguro como requisito para cubrir los posibles daños ambientales en las actividades riesgosas, específicamente señala el Artículo 22 de dicha ley. Asimismo, define
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Despu s de mucho tiempo
2019-05-05
Después de mucho tiempo, Argentina dio una respuesta positiva a la decisión política, tanto de Colombia como de Perú, de reactivar las relaciones bilaterales. En cambio, en el nexo con Chile, Argentina no tenía que dar respuestas sino buscar alternativas para tratar de salir del progresivo debilitam
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Regarding the expression of NKp NCR
2019-05-05
Regarding the expression of NKp46/NCR1 (Fig. 1A and B), both increased and decreased expression are observed depending on patients. Interestingly, the expression of the inducible molecule NKp44/NCR2 is clearly induced in 3 patients (PT1, PT2 and PT5) both regarding the percentage and the MFI. In con
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HBeAg positive patients older than years with
2019-05-05
HBeAg-positive patients older than 40 years with persistently high or high to normal ALT levels may be diagnosed with significant hepatic necroinflammation or fibrosis. During treatment, the clinical significance of timing of HBeAg loss or seroconversion remains unclear. However, a longer duration o
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Introduction Cancer therapy has evolved throughout the decad
2019-05-05
Introduction Cancer therapy has evolved throughout the decades and is beginning to branch off into new and exciting fields including immunotherapy. The hope of this new field stems from the lack of success of chemotherapy in general. Chemotherapy\'s cytotoxic characteristics were regarded as one of
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