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Gastrointestinal tone can be effectively modulated by cholin
2019-07-01
Gastrointestinal tone can be effectively modulated by cholinesterase inhibitors. As parasympathetic fibers release Butyrolactone 3 structure to contract the circular and longitudinal intestinal muscles, AChE inhibition can facilitate those actions. Postoperative ileus (delayed gastric emptying afte
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It is well known that Doxorubicin
2019-07-01
It is well known that Doxorubicin-induced cardiotoxicity occurs via p53-mediated apoptosis (Lorusso et al., 2007). However, there are few studies elucidating the mechanism of HFS induced by PLD. We found that PLD induces keratinocyte apoptosis in a very low dose, and the damage induced by PLD cannot
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In terms of outcome based assessments
2019-07-01
In terms of outcome-based assessments, we analyzed the primary outcomes in both the 7-day and in-hospital mortality, to evaluate further whether the cause of death would be related to acute illness or chronic comorbidities, and furthermore to ensure care quality in both units. Illness severity and t
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The immunohistochemistry showed infiltration of CD
2019-07-01
The immunohistochemistry showed infiltration of CD3+ T cells in dermis and few in the epidermis. The double staining of vitiligo biopsies by CD3+ and CD4+ showed that most of CD3+ cells are also CD4+. Whereas, CD3+/CD8+ are present in leading edge and lesional vitiligo skin and showing a mixture of
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Bacterial LPS stimulates monocytes and tissue
2019-07-01
Bacterial LPS stimulates monocytes and tissue macrophages to release TNF-α and IL-1, which then stimulate secondary response cytokines, including IL-6. In addition to hematopoietic cells, IL-6 is synthesized by many different types of nonhematopoietic cells, including endothelium, lasting for an ext
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Accordingly blockade of TL A Fas L TLR
2019-07-01
Accordingly, blockade of TL1A/Fas-L/TLR4 cascades and inhibition of the M1/Th1 differentiation associated with DcR3 might potentially rescue hepatic IR injury. However, the contribution of TL1A/Fas-L/TLR4 on the M1/M2 and Th1/Th2 balances, as well as pathogenic liver IR injury had never previously b
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One day after implantation diaphragmatic stimulation
2019-07-01
One day after implantation, diaphragmatic stimulation was observed when the patient was in the seated position, and it could not be resolved by reprogramming the device. We decided to replace the LV lead; however, there were no other vein branches suitable for CRT in the lateral region of the LV (Fi
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br Introduction Patients with advanced
2019-07-01
Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly
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Preamble The J wave syndromes JWSs consisting
2019-07-01
Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology citco of over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brugada in 1992 [1].
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br The translational pipeline in biomedicine from bench to
2019-07-01
The translational pipeline in biomedicine (from bench to bedside) focused the attention of the global research gli protein on delivery of results to patients. The notion was rapidly accepted, as shown by the training of researchers in translational approaches, the establishment of translational r
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(+)-Aphidicolin El prop sito es a partir del estudio de la
2019-07-01
El propósito es, (+)-Aphidicolin partir del “estudio de la vida, y las relaciones, los vínculos de poder”, ir descubriendo “cómo construir un movimiento que democratice hacia adentro”, sin tener como meta una presencia en las dinámicas instituidas de participación política institucional. Se trata, e
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The patient began CODOX M IVAC with rituximab PET and
2019-07-01
The patient began CODOX-M/IVAC with rituximab [2]. PET and BM after 2 cycles showed complete remission (CR) and this was confirmed 3 and 6 months later after he completed the full treatment course. There was no delay in administration of each cycle (average: 19 days, 16–21). Eight months after thera
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cpi-613 Recently a reciprocal fusion between YPEL yippee lik
2019-07-01
Recently, a reciprocal fusion between YPEL5 (yippee-like 5) and PPP1CB (serine/threonine protein phosphatase-1 beta catalytic subunit) was described to be exclusively expressed in more than 90% of primary CLL samples [5] and not in control samples or samples from patients with other hematological ma
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Therefore other imaging techniques and tools have been evalu
2019-06-29
Therefore, other imaging techniques and tools have been evaluated. The results of this study add to the body of evidence demonstrating the value of SPECT and the need for a multifactorial approach to patient selection for CRT and in evaluating potential predictors of CRT response in non-ischemic pat
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Our patient had an AV interval of approximately
2019-06-29
Our patient had an AV interval of approximately 100ms, reflecting the sensing of low atrial activity. The upper rate in the VVT mode is usually factory set and not programmable. However, it can be modified by programming the ventricular refractory period if necessary. This L-a-Hydroxyglutaric acid d
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