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br Introduction The period around birth is
2022-07-14
Introduction The period around birth is a risky time for stroke in infants. Ischemic stroke has been diagnosed in about 1/4000 full-term infants (Nelson and Lynch, 2004) and perinatal stroke represents the second most frequent cause of acute seizures in this age group (Levy et al., 1985). Further
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br Methods br Results br Discussion In
2022-07-14
Methods Results Discussion In the general population BNP has been established as a marker for AG 013736 failure diagnosis. Moreover, there is growing evidence that elevated levels of natriuretic-peptides may improve CV risk prediction in the general population above traditional risk factors
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The molecular mechanism of gliotransmitter release is not fu
2022-07-14
The molecular mechanism of gliotransmitter release is not fully understood until now, and previous studies have emphasized that the elevation of [Ca2+]i triggers vesicular PF-03814735 of glutamate. Parpura et al. reported that the essential role of Ca2+ release from internal stores in glutamate rele
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In the same research group released a free internet
2022-07-14
In 2017, the same research group released a free internet accessible database (HemeOxDB, http://www.researchdsf.unict.it/hemeoxdb), to make it easier the analysis of the literature and, consequently, the design of potent and selective HO-1 inhibitors. The database reported the entire set of HO-1 and
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88 3 mg Roughly million people who are currently infected
2022-07-13
Roughly 15 million people who are currently infected with HBV are co-infected with the hepatitis D virus (HDV) (WHO, 2017b). The superinfection not only leads to more severe liver damage and early onset of cirrhosis, but also to a higher mortality than HBV mono-infection (Rizzetto, 1983; WHO, 2017b)
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Aspartame l aspartyl l phenylalanine methylester is a
2022-07-13
Aspartame (l-aspartyl l-phenylalanine methylester) is a dipeptide artificial sweetener that is widely used as a non-nutritive sweetener in various food products [1]. The increased market of dietary products and the development of new synthetic sweetening compounds have not been sufficiently explored
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It was revealed that various injured or infected organs of
2022-07-13
It was revealed that various injured or infected organs of Hippeastrum produce a mixture of an orange-colored chalcone and flavans which can be oxidized to red-colored dimer (Wilmowicz et al., 2014, Wink and Lehmann, 1996), preventing the penetration of injured tissues by Phoma narcissi, Botrytis ci
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br Material and methods br
2022-07-13
Material and methods Results and discussion Unlike many fruits such as bananas and tomatoes, known as climacteric fruits, in which ripening is regulated by a burst of phosphatase inhibitor biosynthesis and an increase in respiration, pepper fruits, which do not follow this pattern, are called
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The compounds described in this paper were prepared using a
2022-07-13
The compounds described in this paper were prepared using a modular approach that allowed diversification of R or R at the final step (). Route A involved amide coupling of -butyl 4-(methylamino)piperidine-1-carboxylate with phenyl acetic acids (step a) using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-m
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Alverine Citrate In this study three potential Otx binding
2022-07-13
In this study, three potential Otx-2 Alverine Citrate were found in the promoter region of the sheep GnRH gene: −1786 bp to −1770 bp, −825 bp to −819 bp, and − 529 bp to −523 bp. Combined with the results of the double-luciferase assay, it could be inferred that the binding site of Otx-2 in the cor
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The GlyR is pentameric with each subunit
2022-07-13
The GlyR is pentameric, with each subunit consisting of an extracellular ligand binding domain (LBD), four transmembrane (TM) segments, and a large intracellular loop between TM3 and TM4. Binding of neurotransmitter produces conformational changes that are rapidly transmitted to the membrane-spannin
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This resembles a vicious cycle
2022-07-13
This resembles a vicious cycle since BBB disruption and inflammation are thought to be caused by epilepsy, but other contributing factors are also known to be their cause, such as peripheral infection, autoimmunity, 8380 trauma and stroke that also underlie epilepsy [18]. Additional triggers that st
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br Characterization and regional localization
2022-07-13
Characterization and regional localization of Glu transporters Molecular studies led to the description of five subtypes of plasma membrane Glu transporters termed in accordance to their human or rodent origin (Kanai and Hediger, 1992, Pines et al., 1992, Storck et al., 1992). In humans, these tr
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In the present study we characterized
2022-07-13
In the present study, we characterized the expression of glucose transporters in the developing and adult mouse lens and showed that GLUT1 is the primary transporter expressed in the lens epithelium. We found that mice with a homozygous deletion of Slc2a1 from the lens epithelium developed cataracts
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Up to now the research about the effect of
2022-07-13
Up to now, the research about the effect of PAs on inhibiting carbohydrase activity in vitro or reducing blood sugar level in vivo was mainly reported in PAs from grape seeds, Lepisanthes alata (Malay cherry) leaves, sorghum, pomegranate, cranberry and persimmon (Banerji and Banerjee, 2016, Barrett
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